RECENT TREATMENT TACTICS FOR THE PATIENT WITH LUMINAL BREAST CANCER. LITERARY REVIEW

Abstract

Objectives.  The aim of the study was to analyze evidence based data from existing sources, regarding the treatment tactics for the patient with luminal breast cancer.

Material and methods. Google Scholar and PubMed, Central PubMed and international medical literature search engines were used to find evidence based data regarding the treatment tactics for the patient with luminal breast cancer. The following keywords were used for search: “breast cancer”, “luminal subtype”, “estrogen receptor”, “radical mastectomy”.

Results. There were identified 51 scientific publications that reflect current evidence regarding the treatment tactics for the patient with luminal breast cancer. 

Conclusions. The modern treatment of breast cancer is complex and depends on the immunohistochemical characteristics, genetic profile, age, histological results and stage of the tumor. Most breast cancers are diagnosed at an early stage and are hormone positive receptors, therefore adjuvant treatment with hormonotherapy significantly reduces the rate of recurrence and mortality. In the initial stages, combined treatment (surgical and hormonal) has higher survival rates compared to radical mastectomies. According to the latest studies, local radiotherapy can induce immunotherapeutic effects in patients with breast cancer.