MALIGNANT MELANOMA METASTASIS IN THE PANCREAS COMPLICATED BY MECHANICAL JAUNDICE AND UPPER GASTROINTESTINAL BLEEDING (UGB). CLINICAL CASE

Authors

  • Sergiu Revencu State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Chișinău, Republic of Moldova
  • Ion Garștea State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Chișinău, Republic of Moldova
  • Eugen Leahu State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Chișinău, Republic of Moldova
  • Dan Revencu State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Chișinău, Republic of Moldova
  • Sergiu Balan State University of Medicine and Pharmacy “Nicolae Testemiţanu”, Chișinău, Republic of Moldova

DOI:

https://doi.org/10.5281/zenodo.6510203

Keywords:

UGB, melanoma, metastasis, pancreas, duodenopancreatic resection

Abstract

Introduction. Metastases of malignant melanoma in the pancreas, with the development of jaundice, involvement of the duodenum and upper gastrointestinal bleeding are casuistic. Tumor metastases in the pancreas are found in a proportion of 2-5%, and metastases of malignant melanoma in less than 1% of cases. Duodenopancreatic resections single or in complex therapy, resolve complications, increasing survival and improving quality of life. The purpose of the article is to show the resolution of metastatic complications in the cephalopancreas by duodenopancreatic resections.

Case presentation. It is presented a case of a malignant melanoma metastasis in the cephalopancreas, complicated by obstructive jaundice and upper gastrointestinal bleeding.  The 39-year-old patient underwent small bowel resection for bowel obstruction, which was shown to be caused by myeloma metastases in the mesentery lymph nodes. He was hospitalized after one year or mechanical jaundice and upper gastrointestinal bleeding, being diagnosed with melanoma metastasis to the cephalopancreas. There was performed the Whipple procedure (or pancreaticoduodenectomy) followed by an evolution without complications. He has been under surveillance for 18 months. Currently active, in a satisfactory general condition.

Conclusions. Resection of the pancreas with malignant melanoma metastases is possible, though, in a small number of cases. It has a palliative aspect, less radical, the basic operative indication being the jaundice and hemorrhagic complications.

Published

01-05-2022

Issue

Section

CLINICAL CASES

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